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Ticona develops UHMWPE with vitamin E for orthopedic implants

03 Nov '07
3 min read

Ticona has developed two new grades of ultrahigh molecular weight polyethylene (UHMWPE) containing vitamin E (alpha-tocopherol). The addition of this biocompatible antioxidant provides these new grades with effective oxidation stability. The aim is to further extend the lifetime of orthopedic implants.

Hips, knees, shoulders, spine components, elbows or ankles – more and more people are now relying on synthetic orthopedic joints or joint components because they offer high functionality over a long lifetime. Because of the excellent combination of properties, including biocompatibility, high abrasion resistance, impact strength and fatigue and crack resistance, GUR UHMWPE polymers from Ticona have long been the gold standard for such applications.

Implants made from this material need to be sterilized. When sterilization is accomplished by modern irradiation techniques, stabilization with vitamin E is intended to reduce susceptibility to oxidation in this process. The biocompatible antioxidant has already been used for many years in the food industry.

The physiological compatibility of GUR polymers has been proven since the 1960s. This thermoplastic meets the standards of the United States Pharmacopeia (USP), Class IV, and is approved by the US Food and Drug Administration (FDA). In addition, GUR polymers meet the requirements of standard ASTM F648 published by the American Society for Testing and Materials and ISO standard 5834-1/-2 for starting materials and semi-finished products.

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