More specifically, HSS combining (melanin-producing) melanocytes from naturally dark skin with keratinocytes from naturally dark skin produces more melanin on the surface of the skin than HSS combining melanocytes from naturally dark skin with keratinocytes from naturally light skin.
This discovery raises the possibility of skin color control via the keratinocytes, which are more numerous (comprising 96% of the epidermis) and more accessible (occupying the surface layers) than melanocytes.
It is expected that the research findings will be applied in developing skin-lightening and tanning products, with the goal of attaining a youthful and attractive appearance through controlled skin color.